In order to realize the benefits of PhyTip columns for protein purification and enrichment, PhyNexus has developed the PhyTip semi-automated ME and fully automated MEA Purification Systems as the platforms of choice for purification of up to 96 samples. When used with the PhyNexus Operating Software, these systems offer a range of flow rates that maximize the purification and enrichment efficiency of the various affinity resins available for PhyTip columns. These unique systems allow for reproducible positioning of the PhyTip columns into the sample solution, wash buffer(s) and finally the elution buffer used for enrichment. By maintaining the optimum position, the system is able to accurately deliver the programmed volumes of liquids through each column.
Whether separations are performed a few times a week or a few thousand times a day, PhyTip columns may be used with manual pipettes, the ME or MEA purification systems, or other commercially available robotic systems. The PhyTip ME Purification Systems allow for complete flexibility and semi-automated processing of 1-12 samples at a time. The MEA robot fills the productivity gap between the ME semi automated instruments and 96 channel capability robots.
